3 ms·
It's definitely not 1:1, but the mRNA degrades fairly quickly at body temperature (thus, 2 doses). Here is a study of the effects - https://www.nejm.org/doi/fu
by arrosenberg 6y ago
It's definitely not 1:1, but the mRNA degrades fairly quickly at body temperature (thus, 2 doses).
Here is a study of the effects - https://www.nejm.org/doi/full/10.1056/NEJMoa2024671 https://www.nejm.org/doi/full/10.1056/NEJMoa2024671.
It doesn't directly address your question, but it does show how the vaccine performs to control (labeled pbs) in terms of viral load and immune system activity when challenged with a dose of the virus.
- shellfishgene 6y agoThe mRNA produced for the vaccines have various modifications that cause greater stability than normal mRNA. The two shots have nothing to do with mRNA stability, they improve immunity, as in any other vaccine given in two or three shots.