Not to sound trite but: Start a project. You will learn all sorts of things about project management in a software development setting. Source code organizati

Not to sound trite but: Start a project. You will learn all sorts of things about project management in a software development setting. Source code organization, etc. You will gain domain knowledge of whatever technology stack you decide to deploy against, be that desktop software or some kind of web based server stack. You will find challenges where you least expect them (typically where you've made a poor assumption) and at the end you'll have something to show for your effort that will be much more effect than a few lines on a resume. As I am not deeply involved in bio-related software dev I'm afraid I can't offer you any kind of concrete project ideas. The last time I did anything biology related was when played around with visualizing genome datasets.