All first 5 to be developed vaccines are pretty successful. So don't think survivor bias applies here. Also, what exactly are those catastrophic side effects? A

All first 5 to be developed vaccines are pretty successful. So don't think survivor bias applies here. Also, what exactly are those catastrophic side effects? All the cases of "vaccine gone wrong" are pretty mild and most of them don't apply to BionTech/Moderna vaccines (since it doesn't include virus) or related to product problems, which don't depend on trials. If vaccines were started to be used after phase 2, thousands and thousand of lives could be saved. I think it's worth discussing. Especially with these new mRNA vaccines, where new one can be created within a month, it could be a new way to battle upcoming pandemics.