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We’ve got a very limited understanding of biology. Ask any kind of researcher and they’ll tell you we need more data, i.e. more experiments. Also, there’s Illum
by f6v 6y ago
We’ve got a very limited understanding of biology. Ask any kind of researcher and they’ll tell you we need more data, i.e. more experiments. Also, there’s Illumina monopoly in sequencing market, we desperately need competition for genetics to become accessible to general population.
- ta988 6y agoYou can buy a nanopore, no need to go with an Illumina. You can clearly do genomics at home with this.
- f6v 6y agoNanopore is a different kind of instrument and absolute majority of cutting-edge protocols rely on Illumina chemistry. Just no way of escaping it if you're doing science.
- the_only_law 6y agoI briefly looked at a couple of dirt cheap biology programs near me because I used to love biology and it was something different. Then I looked at the salaries working in the field and kinda just stopped.
- Balgair 6y agoIt's a supply and demand issue, just like in nursing. There are a lot of bio undergrads out there in the US, and as such the wages are depressed. That said, with higher degrees comes higher wages. And with 'outsider' skill sets comes higher wages. Things like programming, EE, and management-skills will get you a better job in bio. Honestly, most bio people don't have anything past Calculus 1, so if you even have Linear Algebra, you're much ahead of the group, let alone Diff. Eqs. or some real Stats classes. Granted, these salaries not near SWE jobs, but you're not working on dog-walking-apps, you're working on heart conditions and health issues. The effort, inherently, is compensation to those doing it.
- Balgair 6y agoThere's a poster out there of all the relevant chemistry of human mitochondria. It's a pretty big poster, about a square meter of paper. Every pore and protein's function is represented. The Kreb's Cycle is in a corner of this thing. All the chain reactions are there, with lines trying to vainly connect it all together. The font on it is ~9 pt., I think. And it's double sided. I can't find a good link on Google, but other biologists will know what I'm talking about. That poster is the result of ~70 years of hardcore work and blood and sweat of ~10k+ people on the human mitochondria. That poster alone is worth billions of dollar of research and will likely save billions of lives. And it's just the normal functions of the human mitochondria. One of many organelles in a 'typical' human cell. I'm not aware of any attempts to produce such a thing for something as complicated as the ER or the nucleus. Our understanding of bio is very much limited. But I want to stress that Bio is complicated much more beyond what anyone thinks it is. There is a good quote to help grok the ocean we are looking into: Imagine a flashy spaceship lands in your backyard. The door opens and you are invited to investigate everything to see what you can learn. The technology is clearly millions of years beyond what we can make. This is biology. –Bert Hubert, “Our Amazing Immune System”
- hak8or 6y agoCan someone find this poster? I would utterly love to buy it and hang it somewhere, but I can't find it when googling.
- ArmandGrillet 6y agoThe two posters on this website look similar to the provided description: http://biochemical-pathways.com/#/map/1 http://biochemical-pathways.com/#/map/1
- Balgair 6y agoThis is exactly it! Thank you for the find!
- mprovost 6y agoRoche will send you a free copy! https://www.roche.com/sustainability/philanthropy/science_education/pathways/pathways-ordering.htm https://www.roche.com/sustainability/philanthropy/science_ed...
- shellfishgene 6y agoThere is Illumina competition now with BGI Nanoball sequencing...