3 ms·
My understanding was that there was enough scale at the main dosing regimen, however the 'mistake' dosing regimen showed additional promise.
by Closi 6y ago
My understanding was that there was enough scale at the main dosing regimen, however the 'mistake' dosing regimen showed additional promise.
- randcraw 6y agoTrue, except for patients age 55+. They did not receive the initial half-concentration dose. That's almost certainly why those receiving the half-concentration dose experienced much higher efficacy (90% vs 62%) — they were younger and had fewer co-morbidities.
- addicted 6y agoNo, the mistake is not showing additional promise. The “mistake” is a clue that the study was completely botched.
- Closi 6y agoNot completely botched, they approached the regulator with an error and followed their advice on how to continue. The regulators advice was how the final results were presented in the published paper (i.e. with the accidental dosing as a separate group).