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There was an HIV vaccine trial a few years ago that was adenovirus based, where patients who got the vaccine ended up with a _higher_ rate of infection than tho

There was an HIV vaccine trial a few years ago that was adenovirus based, where patients who got the vaccine ended up with a _higher_ rate of infection than those in the control group. It was a major disaster. The mechanism was believed to be those who'd had the adenovirus previously were at increased risk. The AZ vaccine uses a modified chimp adenovirus people have not been exposed to in order to reduce this kind of risk, but the Russian vaccine uses the same adenovirus as the failed HIV vaccine trial.

Jabbles 6y ago
You should include your sources to distinguish your comment from the anti-vax noise: HIV original vaccine: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585831/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585831/ As relates to Covid: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571904/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571904/