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That’s really interesting. I have a bottle of probably 300 acetominophen caplets from Costco, it’s my go-to hangover cure. Ibuprofen and acetaminophen are incre

by cmckn 6y ago

That’s really interesting. I have a bottle of probably 300 acetominophen caplets from Costco, it’s my go-to hangover cure. Ibuprofen and acetaminophen are incredibly common in the US.

DominikPeters 6y ago
Yeah, US bottles seem crazy to me, for drugs where overdose is lethal. I think the theory behind the UK pack size restriction is that suicide attempts are often spontaneous, so it's life-saving not to have a lethal amount in the house. Also, accidentally popping hundreds of pills out of the blister packaging (rather than a bottle) is pretty unlikely. The restrictions seem to work, with a 40% reduction in paracetamol-related deaths: https://www.nhs.uk/news/medication/smaller-paracetamol-packs-may-have-reduced-deaths/ https://www.nhs.uk/news/medication/smaller-paracetamol-packs...
- fallingfrog 6y ago
  What’s really funny is that if you go to Amsterdam, you can get paracetamol in a quick dissolving pill that works much faster than the really hard ones you get in the states, but it’s in a bubble package and fewer doses so it’s harder to commit suicide with. But in the states you only get the hard pills, which are harder to crush and use to make illicit drugs out of, but in unlimited amounts. So.. we don’t care if you kill yourselves, as long as you don’t have any fun doing it?
  - Arubis 6y ago
    > we don’t care if you kill yourselves, as long as you don’t have any fun doing it? This is actually a good summary. As mentioned in sibling threads, most pharmaceuticals that could potentially be enjoyable are formulated stateside in combination with things that will either make you feel terrible or outright kill you at high enough doses.
tasty_freeze 6y ago
I'd say if you need that much tylenol for your hangovers, the alcohol consumption is a far bigger worry than the side effects of the tylenol.
- hombre_fatal 6y ago
  You're missing the necessary information to make that assumption. Though the temptation to judge others is an inherent human trait of sanctimony. I bought a massive sack of kosher salt because it was a good deal. It's a stupid amount. Doesn't mean I overdose on salt with every meal, it's going to last me a long, long time. Might become a family heirloom. You'd be silly to lecture me about salt intake.
  - the_only_law 6y ago
    To add, people respond to alcohol differently due to genetics, metabolism, etc. I can wake up the next day with a ponding headache even after a seemingly small amount of drinks to some people, especially if I’m poorly hydrated in general,
    - cmckn 6y ago
      A couple glasses of water before bed works at least as well as a pill the next morning, in my experience. Hangovers are one of the main ways I feel myself getting old! Haha
- cmckn 6y ago
  Bit confused by your comment—Costco is a big box store. I paid maybe $10 for the bottle. I’m not taking it daily, nor do I take more than a standard amount. I was just commenting that it’s sold in much larger quantities here, not that I’m abusing acetaminophen or alcohol.
scaladev 6y ago
Are you sure it's safe? Paracetamol has high hepatotoxic effects when taken with (or soon after consumption of) alcohol. It's probably best to ask a doctor when you have a chance.
- deleted 6y ago
  [deleted]
- cmckn 6y ago
  I take a standard adult dose in the morning, 6-8 hours after I stop drinking and after plenty of water. I’m not worried about it. Also, to be fair, I usually take ibuprofen. Acetaminophen hits different though, sometimes it’s what you need.

by cmckn 6y ago

That’s really interesting. I have a bottle of probably 300 acetominophen caplets from Costco, it’s my go-to hangover cure. Ibuprofen and acetaminophen are incredibly common in the US.

DominikPeters 6y ago

Yeah, US bottles seem crazy to me, for drugs where overdose is lethal. I think the theory behind the UK pack size restriction is that suicide attempts are often spontaneous, so it's life-saving not to have a lethal amount in the house. Also, accidentally popping hundreds of pills out of the blister packaging (rather than a bottle) is pretty unlikely. The restrictions seem to work, with a 40% reduction in paracetamol-related deaths: https://www.nhs.uk/news/medication/smaller-paracetamol-packs-may-have-reduced-deaths/ https://www.nhs.uk/news/medication/smaller-paracetamol-packs...

fallingfrog 6y ago
What’s really funny is that if you go to Amsterdam, you can get paracetamol in a quick dissolving pill that works much faster than the really hard ones you get in the states, but it’s in a bubble package and fewer doses so it’s harder to commit suicide with. But in the states you only get the hard pills, which are harder to crush and use to make illicit drugs out of, but in unlimited amounts. So.. we don’t care if you kill yourselves, as long as you don’t have any fun doing it?
- Arubis 6y ago
  > we don’t care if you kill yourselves, as long as you don’t have any fun doing it? This is actually a good summary. As mentioned in sibling threads, most pharmaceuticals that could potentially be enjoyable are formulated stateside in combination with things that will either make you feel terrible or outright kill you at high enough doses.

tasty_freeze 6y ago

I'd say if you need that much tylenol for your hangovers, the alcohol consumption is a far bigger worry than the side effects of the tylenol.

hombre_fatal 6y ago
You're missing the necessary information to make that assumption. Though the temptation to judge others is an inherent human trait of sanctimony. I bought a massive sack of kosher salt because it was a good deal. It's a stupid amount. Doesn't mean I overdose on salt with every meal, it's going to last me a long, long time. Might become a family heirloom. You'd be silly to lecture me about salt intake.
- the_only_law 6y ago
  To add, people respond to alcohol differently due to genetics, metabolism, etc. I can wake up the next day with a ponding headache even after a seemingly small amount of drinks to some people, especially if I’m poorly hydrated in general,
  - cmckn 6y ago
    A couple glasses of water before bed works at least as well as a pill the next morning, in my experience. Hangovers are one of the main ways I feel myself getting old! Haha
cmckn 6y ago
Bit confused by your comment—Costco is a big box store. I paid maybe $10 for the bottle. I’m not taking it daily, nor do I take more than a standard amount. I was just commenting that it’s sold in much larger quantities here, not that I’m abusing acetaminophen or alcohol.

scaladev 6y ago

Are you sure it's safe? Paracetamol has high hepatotoxic effects when taken with (or soon after consumption of) alcohol. It's probably best to ask a doctor when you have a chance.

deleted 6y ago
[deleted]
cmckn 6y ago
I take a standard adult dose in the morning, 6-8 hours after I stop drinking and after plenty of water. I’m not worried about it. Also, to be fair, I usually take ibuprofen. Acetaminophen hits different though, sometimes it’s what you need.