3 ms·
There is incredible potential out there, potentially dozens of useful treatments that are safe and cheap, and all we have to do is repurpose them. Consider tha
by Dumblydorr 6y ago
There is incredible potential out there, potentially dozens of useful treatments that are safe and cheap, and all we have to do is repurpose them.
Consider that new drugs cost 1 to 2 billion to come to market, needing extensive tests in petri dishes, cells, animals, young male human volunteers, and then mass drug trials. It is very slow and challenging work to find new drug molecules that are both safe and effective.
But, there are hundreds of disorders, we can't test all safe drugs for effective actions against all disorders. If we have great repurposing, probably through mass automation of tests and computer modeling, then we can make a gold mine of already existing gold nuggets.
This was true of dexamethasone for covid, seems true of loperamide, and could be true for dozens of other compounds already in our pharmacy and medicine cabinet. This is the biggest opportunity in drug development, and HN has technical, computational talent, so consider this area!!!
- adamredwoods 6y agoWhere is a good area to begin studying computer modeling/testing for pharma?
- gregwebs 6y agoHow would you turn this into a gold mine? As I understand it the opportunity for off-label drug use is limited. Although the off-label drug will be cheaper to bring to market the patent will expire and then you can no longer recoup the enormous cost of clinical trials.