The paper ATF4 links ER stress with reticulophagy in glioblastoma cells [1]: > ...several studies have shown the induction of autophagic cell death (ACD) by na

The paper ATF4 links ER stress with reticulophagy in glioblastoma cells [1]: > ...several studies have shown the induction of autophagic cell death (ACD) by natural compounds or Food and Drug Administration-approved drugs in multiple cancer cell lines. Among these, glioblastomas seem to be particularly vulnerable to the induction of ACD, thus highlighting ACD induction in the context of glioblastoma as an attractive therapeutic strategy to selectively trigger cancer cell death. Glioblastoma [2], "also known as glioblastoma multiforme (GBM), is the most aggressive type of cancer that begins within the brain." Autophagy [3] "is the natural, regulated mechanism of the cell that removes unnecessary or dysfunctional components." [1] https://www.tandfonline.com/doi/full/10.1080/15548627.2020.1827780 https://www.tandfonline.com/doi/full/10.1080/15548627.2020.1... [2] https://en.wikipedia.org/wiki/Glioblastoma https://en.wikipedia.org/wiki/Glioblastoma [3] https://en.wikipedia.org/wiki/Autophagy https://en.wikipedia.org/wiki/Autophagy