You can. I did: a Logitech BRIO 4k. I used it mainly as a document camera to deliver lectures from home. I should now probably avoid using fingerprint reader

You can. I did: a Logitech BRIO 4k. I used it mainly as a document camera to deliver lectures from home. I should now probably avoid using fingerprint reader unlock systems, as you could probably pretty easily get my fingerprints from frames in the video (Mythbusters demonstrated even a printout can work). That will be a good enough webcam for years to come, though I expect my next DSLR upgrade to provide a whole other class of option at some point. Relying on the mics built into a webcam seems pretty silly, though.