4 ms·
I'm not a virologist but this is clickbait I think, it does not take long to synthesis fragments of the spike protein for a traditional vaccine either or progra
by l33tman 6y ago
I'm not a virologist but this is clickbait I think, it does not take long to synthesis fragments of the spike protein for a traditional vaccine either or program the rhinovirus vector in a more modern vaccine. I don't think that really is the bottleneck. You still need a LOT of testing as the viral antigen you are trying to vaccinate against can have similarities to human proteins for example, and the antigen might simply be a bad antigen for immunization - and this requires a lot of testing and studies.
The normal yearly influenza vaccines are also fast for example because they are well known platforms and also the antigens repeat historically and are thus (relatively) well tested.
I guess my point is that the problem of the vector to get the antigen in contact with the immune system is orthogonal to the problem of selecting the antigen for overall cross reactivity and efficiency and the latter is still a difficult and timeconsuming problem.