6 ms·

Taking bets that caffeine consumption will be found to be a comorbidity.

dilyevsky 6y ago
There’s some research that actually found the opposite (also for parkinsons)
PragmaticPulp 6y ago
Studies suggest it might be neutral or even protective in Alzheimer's: https://pubmed.ncbi.nlm.nih.gov/20182054/ https://pubmed.ncbi.nlm.nih.gov/20182054/ > In the CAIDE study, coffee drinking of 3-5 cups per day at midlife was associated with a decreased risk of dementia/AD by about 65% at late-life. In conclusion, coffee drinking may be associated with a decreased risk of dementia/AD. This may be mediated by caffeine and/or other mechanisms like antioxidant capacity and increased insulin sensitivity. Not all studies are this positive. Note that sleep deprivation is still a risk factor, with or without the aid of caffeine.
silverpepsi 6y ago
I sure hope not. I increased my caffeine consumption intentionally 5x in the past decade because alzheimer's runs in both sides of the family.
- kevmo 6y ago
  I'm not a doctor, just a person who also has Alzheimer's in his family, so I've thought and read a lot about it. My recipe is basically: Sleep enough, exercise (especially outside), eat right, make sure your brain is active and engaged on a regular basis (read real books, challenge yourself by getting out of your intellectual comfort zone). Studies show that coffee is good for Alzheimer's, so as long as you're not using it to stay awake when you need sleep, it's probably fine.
  - Darkphibre 6y ago
    Is it coffee? Or is it caffeine (i.e. tea, etc.)? I consume around 500-1000mg of caffeine a day (very carefully timed so as not to get jitters). I can't handle a higher dose of Adderall XR, so I've embraced my higher caffeine intakes as a way to soothe the mind. That said, I don't care for the flavor of coffee, so I typically consume it via Red Bull/5hr/tablet form.
    - kgin 6y ago
      This is a separate in-vitro study that seems to suggest it's not the caffeine that is helping https://www.frontiersin.org/articles/10.3389/fnins.2018.00735/full https://www.frontiersin.org/articles/10.3389/fnins.2018.0073...
      - Darkphibre 6y ago
        Thank you!
schwartzworld 6y ago
Or parenting for that matter.

There’s some research that actually found the opposite (also for parkinsons)

Studies suggest it might be neutral or even protective in Alzheimer's: https://pubmed.ncbi.nlm.nih.gov/20182054/ https://pubmed.ncbi.nlm.nih.gov/20182054/ > In the CAIDE study, coffee drinking of 3-5 cups per day at midlife was associated with a decreased risk of dementia/AD by about 65% at late-life. In conclusion, coffee drinking may be associated with a decreased risk of dementia/AD. This may be mediated by caffeine and/or other mechanisms like antioxidant capacity and increased insulin sensitivity. Not all studies are this positive. Note that sleep deprivation is still a risk factor, with or without the aid of caffeine.

silverpepsi 6y ago

I sure hope not. I increased my caffeine consumption intentionally 5x in the past decade because alzheimer's runs in both sides of the family.

kevmo 6y ago
I'm not a doctor, just a person who also has Alzheimer's in his family, so I've thought and read a lot about it. My recipe is basically: Sleep enough, exercise (especially outside), eat right, make sure your brain is active and engaged on a regular basis (read real books, challenge yourself by getting out of your intellectual comfort zone). Studies show that coffee is good for Alzheimer's, so as long as you're not using it to stay awake when you need sleep, it's probably fine.
- Darkphibre 6y ago
  Is it coffee? Or is it caffeine (i.e. tea, etc.)? I consume around 500-1000mg of caffeine a day (very carefully timed so as not to get jitters). I can't handle a higher dose of Adderall XR, so I've embraced my higher caffeine intakes as a way to soothe the mind. That said, I don't care for the flavor of coffee, so I typically consume it via Red Bull/5hr/tablet form.
  - kgin 6y ago
    This is a separate in-vitro study that seems to suggest it's not the caffeine that is helping https://www.frontiersin.org/articles/10.3389/fnins.2018.00735/full https://www.frontiersin.org/articles/10.3389/fnins.2018.0073...
    - Darkphibre 6y ago
      Thank you!

schwartzworld 6y ago

Or parenting for that matter.