I've used both approaches, GiST in PG and S2 in Mongo, and I feel that S2 has given me more tools to do queries like "which polygons contain this single point?"

I've used both approaches, GiST in PG and S2 in Mongo, and I feel that S2 has given me more tools to do queries like "which polygons contain this single point?" efficiently in my use case.