4 ms·

I'm very weary of this approval. This is the first messenger RNA .. thing (this isn't a vaccine; not like any attenuated or inactivated virus vaccines that have

I'm very weary of this approval. This is the first messenger RNA .. thing (this isn't a vaccine; not like any attenuated or inactivated virus vaccines that have come before it. This is something very different in the way it works). There are no Longitudinal studies. This will be a significant increased risk for people under 40. We shouldn't see to fast track any drug, vaccine or treatment outside of the normal process. I wish the inhaled steroid controlled studies had completed because I was curious of that would have been a useful treatment (a lot of doctors are using them off label) and we wouldn't need something this untested. Fast tracking medications is how mistakes are made. Let's be critical of how these emergency powers are used.

divbzero 6y ago
No mRNA vaccine has been approved before, but from clinical trials of mRNA vaccines dating back to 2008 [1] there’s evidence of short-term side effects but no reason to suspect long-term safety concerns. mRNA vaccines don’t present the risk that attenuated vaccines pose to immunocompromised individuals or pregnant women, and they don’t stay in the body long enough to be a long-term threat. We can’t guarantee 100% because our bodies are complex, but I wouldn’t characterize it as “significant increased risk” for people under (or over) 40. [1]: https://www.nature.com/articles/nrd.2017.243/tables/2 https://www.nature.com/articles/nrd.2017.243/tables/2