>There are apparently some DNA sequencer machines that only interface with older macs. I used to work in a Human Genome Project lab. Two of the 1990s workhors

>There are apparently some DNA sequencer machines that only interface with older macs. I used to work in a Human Genome Project lab. Two of the 1990s workhorse DNA sequencing machines, the Applied Biosystems models 373 & 377, connected to Mac machines of similar vintage (my recollection is we had a lot of Power Mac 7100s, or at least machines in the 7xxx form factor). IIRC the sequencing instrument had an interface to plug into the LocalTalk port on the Mac, but I might be wrong on this, it's been 20+ years. And the software needed the classic MacOS. The ABI 373 and 377 are so old and obsolete at this point that you might find one in your local science museum. I know my city's science museum has a display with an ABI 373 from my old lab. ABI's successor Sanger sequencing machines, models 3700 (1998) and 3730 (2003), had Windows-based companion computers and connected to the instrument via Ethernet port, so you didn't have as much lock-in to super old hardware.