3 ms·
Note that the Pfizer trial at least (and IIRC Moderna as well) excluded people with a history of severe allergies. Which IMO makes sense: why put those people a
by petertodd 6y ago
Note that the Pfizer trial at least (and IIRC Moderna as well) excluded people with a history of severe allergies. Which IMO makes sense: why put those people at risk of a relatively common complication when you don't even know yet if the vaccine is effective? Testing for allergy safety in that small population is something you can do later.
- jfoster 6y agoIf a vaccine contains a known allergen, is giving it to people with severe allergies even a test of anything? Is it possible for allergens to not cause allergies despite being present?
- petertodd 6y agoBy "at risk of a relatively common complication", I'm not trying to say that the vaccines contain any known allergens. I'm not enough of an expert to know if those specific ones do or don't. I'm just saying that people with severe allergies often have allergic reactions to vaccines.
- corty 6y agoIt is entirely possible for an allergen to not cause sensibilisation ans a consequent allergy. It is extremely rare for an allergen you are sensibilized ("allergic") to, not to cause some reaction. But the reaction may vary in strength and symptoms, especially with age and presence of irritants to the immune system. Unfortunately, some vaccines do contain those irritants as active ingredients to improve the function of the vaccine.