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Hey thanks for your comment. Could you describe in more detail how the vaccines are currently being stored in your clinic? How long does the vaccine can remai

Hey thanks for your comment. Could you describe in more detail how the vaccines are currently being stored in your clinic? How long does the vaccine can remain in room temperature, once taken out of clod storage. How many doses have been allocated to your clinic and on an average how many patients do you foresee being vaccinated over a short period of time, let's say a month. Also, are health workers also planning to get vaccinated soon, as they are on the frontline and among most vulnerable to infection. Any other details you would like to share. Thanks again.

dm319 6y ago
I run a specialty clinic for a type of cancer, so it isn't specific for vaccination. However, patients >80 yrs who were attending in person were identified as eligible for the vaccine. They have attended elsewhere in the hospital to receive the vaccine, but my understanding is that it needs -80/70 for storage, and can be moved a total of 4 times before needing to be discarded. I'm afraid I do not know more. Maybe if I wasn't so busy in the clinic I would have read through the info sheets in more detail, but it's always a rush!
bserge 6y ago
I've stated this is my worry with the BioNTech/Fosun vaccine - transporting it safely to Eastern Europe. They can't seem to transport frozen fish properly, I really hope they keep that vaccine in proper conditions, otherwise it'll be rendered useless...
- ceejayoz 6y ago
  It's likely the chain of custody for fish and critical medical supplies will be somewhat different.
  - bserge 6y ago
    I can only hope so. They could very well outsource it to the usual transportation companies, and there isn't much accountability tbh. Oh well, if this one doesn't work, perhaps we can try again with the Oxford vaccine heh
    - ceejayoz 6y ago
      It travels in purpose-built shipping containers, so it shouldn't really matter what the trucker does. https://www.cbsnews.com/news/covid-vaccine-pfizer-distribution-logistical-nightmare/ https://www.cbsnews.com/news/covid-vaccine-pfizer-distributi... > In order to get around that, Pfizer has developed specially built deep-freeze "suitcases" that can be tightly sealed and shipped even in non-refrigerated trucks. https://www.fiercepharma.com/manufacturing/pfizer-designed-new-container-and-plans-to-tap-shipping-companies-for-covid-19 https://www.fiercepharma.com/manufacturing/pfizer-designed-n... indicates they can hold temperature for ten days. They'll likely include seals and simple sensors to detect temperature excursions; for example, my daughter's growth hormone comes with a little piece of plastic that turns permanently pink if it's not stored at the right temperature for a few minutes.
      - bserge 6y ago
        Oh, very interesting. I'm mostly worried about last mile distribution, but yeah, they're not stupid, they took all the necessary measures.
    - watwut 6y ago
      You know, thinking fish and vaccine are treated the same does not show smart understanding of region. Honestly, it shows not understanding it at all. Not that vaccines are about to be flawless. But failure will be different.
dm319 6y ago
Some details: Vaccine storage and preparation The Pfizer/BioNTech coronavirus vaccine has the most difficult storage requirements of all the COVID-19 vaccine candidates currently undergoing trials. Currently, it needs to be stored between -80 to -60°C and has a six-month expiry. Over time and with more data being collected this may change.(4) The vaccine needs to be thawed (for approximately three hours in the fridge or 30 minutes at room temperature) before use and may be stored undiluted at 2–8°C for five days, or for two hours at 25°C prior to use.(4) To prepare the vaccine, it should be diluted using 0.8 mL of sodium chloride 0.9% solution for injection, marked with the date and time, and can then be stored between 2 to 25°C. It must be used within six hours or the remainder discarded.(4) To equalise the pressure in the prepared vial, 1.8 mL of air should be withdrawn using the same syringe for preparation, after which it can be mixed by gently inverting 10 times, producing an off-white solution that is ready to be administered. The vaccines are available in packs of 195. There are five 0.3 mL doses within each vial. In comparison, the Moderna vaccine can be stored at -20°C for up to six months, 30 days at 2 to 8°C and up to 12 hours at 25°C. Each vial contains 10 doses. The AstraZeneca/Oxford vaccine is much simpler than both options, with storage allowance of 2 to 8°C for up to six months. Once open, the vials should be used within six hours stored in a fridge or 48 hours if at room temperature. They are delivered in packs of 10 vials with each vial containing eight or 10 doses of vaccine.

dm319 6y ago

I run a specialty clinic for a type of cancer, so it isn't specific for vaccination. However, patients >80 yrs who were attending in person were identified as eligible for the vaccine. They have attended elsewhere in the hospital to receive the vaccine, but my understanding is that it needs -80/70 for storage, and can be moved a total of 4 times before needing to be discarded. I'm afraid I do not know more. Maybe if I wasn't so busy in the clinic I would have read through the info sheets in more detail, but it's always a rush!

bserge 6y ago

I've stated this is my worry with the BioNTech/Fosun vaccine - transporting it safely to Eastern Europe. They can't seem to transport frozen fish properly, I really hope they keep that vaccine in proper conditions, otherwise it'll be rendered useless...

ceejayoz 6y ago
It's likely the chain of custody for fish and critical medical supplies will be somewhat different.
- bserge 6y ago
  I can only hope so. They could very well outsource it to the usual transportation companies, and there isn't much accountability tbh. Oh well, if this one doesn't work, perhaps we can try again with the Oxford vaccine heh
  - ceejayoz 6y ago
    It travels in purpose-built shipping containers, so it shouldn't really matter what the trucker does. https://www.cbsnews.com/news/covid-vaccine-pfizer-distribution-logistical-nightmare/ https://www.cbsnews.com/news/covid-vaccine-pfizer-distributi... > In order to get around that, Pfizer has developed specially built deep-freeze "suitcases" that can be tightly sealed and shipped even in non-refrigerated trucks. https://www.fiercepharma.com/manufacturing/pfizer-designed-new-container-and-plans-to-tap-shipping-companies-for-covid-19 https://www.fiercepharma.com/manufacturing/pfizer-designed-n... indicates they can hold temperature for ten days. They'll likely include seals and simple sensors to detect temperature excursions; for example, my daughter's growth hormone comes with a little piece of plastic that turns permanently pink if it's not stored at the right temperature for a few minutes.
    - bserge 6y ago
      Oh, very interesting. I'm mostly worried about last mile distribution, but yeah, they're not stupid, they took all the necessary measures.
  - watwut 6y ago
    You know, thinking fish and vaccine are treated the same does not show smart understanding of region. Honestly, it shows not understanding it at all. Not that vaccines are about to be flawless. But failure will be different.

dm319 6y ago

Some details: Vaccine storage and preparation The Pfizer/BioNTech coronavirus vaccine has the most difficult storage requirements of all the COVID-19 vaccine candidates currently undergoing trials. Currently, it needs to be stored between -80 to -60°C and has a six-month expiry. Over time and with more data being collected this may change.(4) The vaccine needs to be thawed (for approximately three hours in the fridge or 30 minutes at room temperature) before use and may be stored undiluted at 2–8°C for five days, or for two hours at 25°C prior to use.(4) To prepare the vaccine, it should be diluted using 0.8 mL of sodium chloride 0.9% solution for injection, marked with the date and time, and can then be stored between 2 to 25°C. It must be used within six hours or the remainder discarded.(4) To equalise the pressure in the prepared vial, 1.8 mL of air should be withdrawn using the same syringe for preparation, after which it can be mixed by gently inverting 10 times, producing an off-white solution that is ready to be administered. The vaccines are available in packs of 195. There are five 0.3 mL doses within each vial. In comparison, the Moderna vaccine can be stored at -20°C for up to six months, 30 days at 2 to 8°C and up to 12 hours at 25°C. Each vial contains 10 doses. The AstraZeneca/Oxford vaccine is much simpler than both options, with storage allowance of 2 to 8°C for up to six months. Once open, the vials should be used within six hours stored in a fridge or 48 hours if at room temperature. They are delivered in packs of 10 vials with each vial containing eight or 10 doses of vaccine.