3 ms·

https://science.sciencemag.org/content/sci/370/6520/1022.full.pdf https://science.sciencemag.org/content/sci/370/6520/1022.ful... 'Public needs to prep for vac

https://science.sciencemag.org/content/sci/370/6520/1022.full.pdf https://science.sciencemag.org/content/sci/370/6520/1022.ful... 'Public needs to prep for vaccine side effects, “Take Tylenol and suck it up,” says one researcher. Fever, aches show vaccine works'.

avsteele 6y ago
Thanks for posting that article. That article is going to be a bad one for convincing people. They overstate COVID lethality and downplay people's worries about the side effects. If this article is representative of the public messaging on the vaccine people are going to start being hesitant to take it. We've already seen some of this. They should instead be talking about the # of people to whom the vaccines have been given and compare their outcomes to accurate COVID stats. This is how I've worked with people who are nervous, but I don't actually have the vaccine trial outcomes (other than # who got COVID) because I don't think they have been published!
timrichard 6y ago
Seeing this post reminded me that when I had the 'flu vaccine a little while back, the Pharmacist advised avoiding Paracetamol (Tylenol?) afterwards in case it reduced the efficacy of the vaccine. A bit of quick Googling turned up study results from a while back suggesting this in relation to childhood vaccines. Just wondering if anyone here with experience in the field has a opinion on whether painkillers like these are best avoided for a short time afterwards.
- Cthulhu_ 6y ago
  Honestly Tylenol is a really fucky one, I've had it once when I was in the US and it got me off my tits. I mean pardon my french but that stuff is something else. And in a lot of cases gratuitous; at best it takes the edge off, for me personally, some paracetamol has the same effect without the side effects of an inability to drive or operate heavy machinery.
  - howlgarnish 6y ago
    Uhh, Tylenol = acetaminophen = paracetamol, it's all the same thing with different names. Did you have one of the Tylenol XX formulations with other active ingredients mixed in, perhaps?
  - vonmoltke 6y ago
    I'm not sure what you took, but plain Tylenol is paracetamol (acetaminophen). It sounds like you may have taken a Tylenol-branded compound medication that added an antihistamine or something like that (there are several acetaminophen-plus over-the-counter medications available).
  - KingMachiavelli 6y ago
    It's possible you had a Tylenol 3 or 4 (or 1,2) which are paracetamol + codeine. Not the strongest painkiller but more than anything OTC.

avsteele 6y ago

Thanks for posting that article. That article is going to be a bad one for convincing people. They overstate COVID lethality and downplay people's worries about the side effects. If this article is representative of the public messaging on the vaccine people are going to start being hesitant to take it. We've already seen some of this. They should instead be talking about the # of people to whom the vaccines have been given and compare their outcomes to accurate COVID stats. This is how I've worked with people who are nervous, but I don't actually have the vaccine trial outcomes (other than # who got COVID) because I don't think they have been published!

timrichard 6y ago

Seeing this post reminded me that when I had the 'flu vaccine a little while back, the Pharmacist advised avoiding Paracetamol (Tylenol?) afterwards in case it reduced the efficacy of the vaccine. A bit of quick Googling turned up study results from a while back suggesting this in relation to childhood vaccines. Just wondering if anyone here with experience in the field has a opinion on whether painkillers like these are best avoided for a short time afterwards.

Cthulhu_ 6y ago
Honestly Tylenol is a really fucky one, I've had it once when I was in the US and it got me off my tits. I mean pardon my french but that stuff is something else. And in a lot of cases gratuitous; at best it takes the edge off, for me personally, some paracetamol has the same effect without the side effects of an inability to drive or operate heavy machinery.
- howlgarnish 6y ago
  Uhh, Tylenol = acetaminophen = paracetamol, it's all the same thing with different names. Did you have one of the Tylenol XX formulations with other active ingredients mixed in, perhaps?
- vonmoltke 6y ago
  I'm not sure what you took, but plain Tylenol is paracetamol (acetaminophen). It sounds like you may have taken a Tylenol-branded compound medication that added an antihistamine or something like that (there are several acetaminophen-plus over-the-counter medications available).
- KingMachiavelli 6y ago
  It's possible you had a Tylenol 3 or 4 (or 1,2) which are paracetamol + codeine. Not the strongest painkiller but more than anything OTC.