I'm personally a big fan of Tailwind + either HTMX or Alpine.js, as it lets me easily generate modular UI components in the back-end using the 'dominate' Python

I'm personally a big fan of Tailwind + either HTMX or Alpine.js, as it lets me easily generate modular UI components in the back-end using the 'dominate' Python library, without having to fuss around too much. (Other frameworks such as React should work as well, I just haven't experimented with them very much so far). Munging these tools together has let me create my own 'distributed back end framework', so I can define back-end logic and front-end logic in the same place, but have the back-end logic run on whichever machine I choose, so e.g. an edge device can send a fragment of UI to a monitoring dashboard. It's all rather nice and I'm very pleased with myself. :-)