just for clarification, I don't know for certain, but it sounds like this is what they are talking about in science-journalism speak: https://news.ycombinator.

just for clarification, I don't know for certain, but it sounds like this is what they are talking about in science-journalism speak: https://news.ycombinator.com/reply?id=25262458&goto=threads%3Fnext%3D25283955%26id%3Ddnautics%2325262458 https://news.ycombinator.com/reply?id=25262458&goto=threads%... So they bootstrapped the phases of the X-ray diffraction pattern with the phases from AlphaFold. This does mean, though, that we must be critical - it is possible that they are converging to nonsense that AlphaFold has generated. To be truly sure, you must have some sort of independent confirmation. Might still be "good enough" depending on what your application is.