Great article. A must-read for any researcher, especially in today's climate of research-mill academic production. It missed a nugget about the H.Pylori bacteri

Great article. A must-read for any researcher, especially in today's climate of research-mill academic production. It missed a nugget about the H.Pylori bacterial cause of stomach ulcer. To prove his hypothesis, Barry Marshall deliberately infected himself with the suspected bacteria. From Wikipedia: "After failed attempts to infect piglets in 1984, Marshall, after having a baseline endoscopy done, drank a broth containing cultured H. pylori, expecting to develop, perhaps years later, an ulcer.[13] He was surprised when, only three days later, he developed vague nausea and halitosis (due to the achlorhydria, there was no acid to kill bacteria in the stomach, and their waste products manifested as bad breath), noticed only by his mother."