3 ms·
> This idea that there is some sort of known risk of a significant issue popping up out of nowhere months or years down the road has no historical precedent. R
by oicu812 6y ago
> This idea that there is some sort of known risk of a significant issue popping up out of nowhere months or years down the road has no historical precedent.
RotaShield [0] was a vaccine for the rotavirus that was released in 1998 and taken off the market in 1999 because of intussusception (bowel folding on itself). 5 cases of this issue occurred during during trials of 10,054 participants, which was deemed "not statistically significant". After the vaccine was licensed and widely distributed, the CDC determined the risk of this complication from the vaccine was 20 to 30 times over the expected risk and the vaccine was pulled off the market.
[0] https://www.cdc.gov/vaccines/vpd-vac/rotavirus/vac-rotashield-historical.htm https://www.cdc.gov/vaccines/vpd-vac/rotavirus/vac-rotashiel...