3 ms·
Depositing a piece of DNA into the nucleus doesn't seem to me to be the same as changing the organism's DNA. If the cell divides, will the daughter cells each h
by QuercusMax 6y ago
Depositing a piece of DNA into the nucleus doesn't seem to me to be the same as changing the organism's DNA. If the cell divides, will the daughter cells each have their own copy of the DNA? It doesn't sound like it to me.
- projektfu 6y agoApparently not. Wild-type adenoviruses seem to prevent cell division while they replicate their DNA on their own until they cause cell lysis to distribute the virions. Adenoviral vectors, on the other hand, leave the free DNA particle in the nucleus where it gets transcribed to RNA but it does not get replicated during mitosis. https://www.genetherapynet.com/viral-vector/adenoviruses.html https://www.genetherapynet.com/viral-vector/adenoviruses.htm...