3 ms·
There’s a lot of reason to suspect that, once the pipeline is set up and validated, tailored RNA will be a lot cheaper than CAR-T. cell culture is hard, whereas
by rflrob 6y ago
There’s a lot of reason to suspect that, once the pipeline is set up and validated, tailored RNA will be a lot cheaper than CAR-T. cell culture is hard, whereas ordering a gene length DNA construct is “only” a few hundred bucks[1]. From there, getting it to mRNA is relatively straightforward. Doing this all medical grade and at scale will be a huge challenge, but should be significantly easier than mass producing CAR-Ts.
[1] https://www.genewiz.com/Public/Services/Gene-Synthesis/TurboGENE https://www.genewiz.com/Public/Services/Gene-Synthesis/Turbo...