4 ms·
I know all that. Besides, one pedantic point - antisense are not the same to typical mRNA, they have thiophosphate group instead of normal phosphate in their ba
by SomeoneFromCA 6y ago
I know all that. Besides, one pedantic point - antisense are not the same to typical mRNA, they have thiophosphate group instead of normal phosphate in their backbone, or some other tweak to make them bind mRNA permanently.
- papa_bear 6y agoSome of us don't know, so the extra detail is appreciated :) Interesting re: the thiophosphate group. It sounds like it just floods your body with some mRNAs complementary to the viral mRNA that blocks it from getting turned into proteins by your cells' ribosomes?
- SomeoneFromCA 6y agoYes, pretty much; almost like NOPing out code in binary patches. However double check about the thiophosphates. I might be wrong. It is either Morpholinos are blockers and thios are promoting destruction of the mRNA or the opposite.