4 ms·
The systems are very complex, but what I see is a few active sites and a bunch of random stuff that happens to hold them in the right spots to control them a bi
by pontifier 6y ago
The systems are very complex, but what I see is a few active sites and a bunch of random stuff that happens to hold them in the right spots to control them a bit.
When reasoning from first principals about immune response, it occured to me that just a few simple processes might be all that is required to explore novel active structures in an organism.
Based partly on my understanding of a study of bacteria that evolved the ability to metabolise a new nutrient, a mutation prior to use is required. The ability to detect a molecule might evolve based on immune responses that use random sequences as "test" active sites that are checked for a specific type of deformation.
If this random sequence deforms immediately, it is discarded because this sequence either deforms automatically or deforms in the presence of something common to "host".
If the test remains negative it is released from the host training environment. If the test pattern deforms some time later, it has detected a "foreign" molecule, and has the potential for use as part of a protein that manipulates this molecule.
Recovering the sequence that detects this new foreign molecule becomes the first step in a hereditary immunity. It also stores this useful sequence for possible use in other "testing" systems. These might bring 3 or 4 of these random test systems together to perform another test.
Simple systems that explore a complex space can come up with seemingly elegant solutions.
The most obvious answer to any of your questions is that, if it worked a different way, that's what the video would show... or there would be no video at all.