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I used to take Sumatriptan, it was a life saver if you got onto it quickly. As I've got older I've had them less and less so no longer need to take it - but I

I used to take Sumatriptan, it was a life saver if you got onto it quickly. As I've got older I've had them less and less so no longer need to take it - but I do recommend people having regular migraines to speak to their Doctor and mention it.

proverbialbunny 6y ago
>I used to take Sumatriptan, it was a life saver if you got onto it quickly. It's the opposite for me. If I take it too early into the migraine it sometimes doesn't work. I will intentionally sit with the migraine for around an hour, or until it gets bad enough, then take sumatriptan and wait the 1h30m to 2 hours for the pain to go away. 2-3 hours of a headache is far better than a day of a full on migraine. Once I take it and it doesn't work it builds up resistance for at least 12 hours, so I'm stuck. I'll take the headache.
- aaronblohowiak 6y ago
  Wow, amazing how varied people's responses to these things are! If I wait too long to take a triptan, its effectiveness reduces quite a bit. I generally try to arrest the migraine with ibuprofen but then take the triptan if it progresses.
  - proverbialbunny 6y ago
    Yep. At this point we shouldn't be thinking of a migraine as a singular thing. Sure, singular symptoms, but there are so many different varied causes and conditions that it can not be a single illness. Sometimes when migraine medicine does not work for me, it's because it's a headache not a migraine. I have some over the counter "migraine strength pain killer" pills which are acetaminophen, asprin, and caffeine, which works most times the migraine medicine does nothing.
- cameronh90 6y ago
  That sounds oddly curious to how psilocybin resistance works. With mushrooms, you have to take the entire dose at the outset. As soon as you can feel it, you now have a strong resistance and any further dose will have a greatly diminished effect.
  - smcleod 6y ago
    I hear that's not the case for everyone ;)
  - proverbialbunny 6y ago
    Yep. It's a triptan, so closer to lsd, but same sort of premise.
aaomidi 6y ago
I've heard this making people a lot slower in reaction times and just general reasoning. I've definitely seen those side effects in my mom.
- proverbialbunny 6y ago
  Time to switch her to a different drug. I haven't had slowed reaction times thankfully.
alkonaut 6y ago
I take it and it’s actually available over the counter (which is odd given how most of the rest of Europe seem to have it only by prescription and Sweden where I am is usually really restrictive). I have tried to figure out why it’s a prescription drug in many countries (reasons could include it’s addictive, has bad side effects, could cause side effects with other drugs, etc), but I haven’t found the reason. Does anyone have any clues on this? I have taken it for a few years and not seen a doctor in that time who I could ask.
- proverbialbunny 6y ago
  In the US they have to apply for it to be over the counter and pay a bunch of money in studies. It's a pretty expensive process. So, in the US it's over the counter if people will seek it out. This way they can charge more. If it's not over the counter it's something generic that people will not go out of their way to a doctor for. In the last 10 years in the US I think the only prescription drugs moved to over the counter is allergy medicine, which seems to fit this pattern: People will not go to a doctor for seasonal allergies typically.

proverbialbunny 6y ago

>I used to take Sumatriptan, it was a life saver if you got onto it quickly. It's the opposite for me. If I take it too early into the migraine it sometimes doesn't work. I will intentionally sit with the migraine for around an hour, or until it gets bad enough, then take sumatriptan and wait the 1h30m to 2 hours for the pain to go away. 2-3 hours of a headache is far better than a day of a full on migraine. Once I take it and it doesn't work it builds up resistance for at least 12 hours, so I'm stuck. I'll take the headache.

aaronblohowiak 6y ago
Wow, amazing how varied people's responses to these things are! If I wait too long to take a triptan, its effectiveness reduces quite a bit. I generally try to arrest the migraine with ibuprofen but then take the triptan if it progresses.
- proverbialbunny 6y ago
  Yep. At this point we shouldn't be thinking of a migraine as a singular thing. Sure, singular symptoms, but there are so many different varied causes and conditions that it can not be a single illness. Sometimes when migraine medicine does not work for me, it's because it's a headache not a migraine. I have some over the counter "migraine strength pain killer" pills which are acetaminophen, asprin, and caffeine, which works most times the migraine medicine does nothing.
cameronh90 6y ago
That sounds oddly curious to how psilocybin resistance works. With mushrooms, you have to take the entire dose at the outset. As soon as you can feel it, you now have a strong resistance and any further dose will have a greatly diminished effect.
- smcleod 6y ago
  I hear that's not the case for everyone ;)
- proverbialbunny 6y ago
  Yep. It's a triptan, so closer to lsd, but same sort of premise.

aaomidi 6y ago

I've heard this making people a lot slower in reaction times and just general reasoning. I've definitely seen those side effects in my mom.

proverbialbunny 6y ago
Time to switch her to a different drug. I haven't had slowed reaction times thankfully.

alkonaut 6y ago

I take it and it’s actually available over the counter (which is odd given how most of the rest of Europe seem to have it only by prescription and Sweden where I am is usually really restrictive). I have tried to figure out why it’s a prescription drug in many countries (reasons could include it’s addictive, has bad side effects, could cause side effects with other drugs, etc), but I haven’t found the reason. Does anyone have any clues on this? I have taken it for a few years and not seen a doctor in that time who I could ask.

proverbialbunny 6y ago
In the US they have to apply for it to be over the counter and pay a bunch of money in studies. It's a pretty expensive process. So, in the US it's over the counter if people will seek it out. This way they can charge more. If it's not over the counter it's something generic that people will not go out of their way to a doctor for. In the last 10 years in the US I think the only prescription drugs moved to over the counter is allergy medicine, which seems to fit this pattern: People will not go to a doctor for seasonal allergies typically.