5 ms·
The 70% is the combined data, so probably the most reliable estimate. For two high doses, they got 62% effectiveness and for one low and one high dose they got
by cuchoi 6y ago
The 70% is the combined data, so probably the most reliable estimate. For two high doses, they got 62% effectiveness and for one low and one high dose they got 90%. They don't know why the latter was more effective.
70% is still a great effectiveness rate, specially for a cheaper and easier to distribute vaccine.
- yread 6y agoThe problem with adenovirus vaccines is that body might build immunity against the adenovirus as well. So, you give one jab, adenovirus infects enough cells and creates enough antigens, immune systems notices and does something about it, but it also notices the adenovirus and makes antibodies against that, too. With the second jab those antibodies immediately neutralize the adenovirus so it can't infect enough cells and make enough of the COVID antigens so the protection is not that strong. The Russian vaccine avoids it by using two different strains of adenovirus for the two jabs
- blueblisters 6y ago> The Russian vaccine avoids it by using two different strains of adenovirus for the two jabs That would complicate manufacturing, logistics and distribution somewhat right?
- cuchoi 6y agoVery interesting! Thanks for sharing