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The two existing mRNA vaccines touted earlier also require two doses.
by afterburner 6y ago
The two existing mRNA vaccines touted earlier also require two doses.
- tzs 6y agoI wonder what happens if you get two doses, but not of the same vaccine?
- vmurthy 6y agoCan you share your thinking around why someone would want to do that given that a combination won't be tested (at-least rigorously). Are you seeing benefits from a logistics point-of-view?
- tzs 6y agoI'm not thinking someone would want to do it. I'm thinking it's going to accidentally happen to some people, at least if there are facilities that offer more than one vaccine.
- jakozaur 6y agoHard to guess. Likely worth investigating, but as secondary priority: 1. You may end up just getting very short and weak immunity, making this approach ineffective. 2. You may get a combination of immunity which can have different efficiency. 3. For some vaccines of same type this works, but is rarely recommended. 4. Mixing partly mRNA and Adenovirus vaccines doesn't to be winning strategy. It is rather more likely to give another vaccine if after two doses you didn't get immunity.
- twic 6y agoIf the vaccines are for the same antigen (eg the spike protein), i would expect that to work fine. Your B cells don't care how the RNA encoding the proteins got into your cells, just what the protein looks like. A caveat here is that different vaccines might use different versions or modifications of the spike protein, in which case it's possible they wouldn't boost each other. This feels unlikely, though, because i think that would also reduce their effectiveness against the real virus.