5 ms·

mRNA vaccines were understood and studied prior to Covid. Covid infections (still) are not understood.

tzs 6y ago
Are there any prior mRNA vaccines that have been approved for human use? Wikipedia (currently...) says this and the Moderna ones would be the first.
- bluGill 6y ago
  There have been a few phase-1 trials in humans. But mostly it is research.
mrosett 6y ago
This isn't entirely true; the technology is still very new.
- floatingatoll 6y ago
  A five second search finds papers on mRNA vaccines from 2018. I see no papers on Covid prior to 2019. In relative terms, as the parent comment was using, we have been studying them longer. I am not arguing that they are well understood, but I imagine most people are filling in that word when they read the comment.
  - abfan1127 6y ago
    We've researched coronaviruses since the 1960s, had MERS and SARS most recently (less recent the 2018). I don't understand why we worry about long term effects of Covid, but not long term effects of mRNA vaccines? Both seem to have things to worry about, with both having different scales. https://www.cdc.gov/coronavirus/types.html https://www.cdc.gov/coronavirus/types.html
just-juan-post 6y ago
100% incorrect. These are the very first mRNA vaccines. Here is Wikiepdia to confirm. [1] You. Are. An. Alpha. Tester. And so is the rest of the world. We all are. https://en.wikipedia.org/wiki/RNA_vaccine https://en.wikipedia.org/wiki/RNA_vaccine "Up until November 2020, no mRNA vaccine, drug, or technology platform, had ever been approved for use in humans, and before 2020, mRNA was only considered a theoretical possibility for effective use in human"
abfan1127 6y ago
why do we get to generalize mRNA vaccines, but not SARS-Cov-2? We've known about coronaviruses since the 1960s, we've had MERS, SARS, and other more recent ones. https://www.cdc.gov/coronavirus/types.html https://www.cdc.gov/coronavirus/types.html I don't think we have long term information on either SARS-Cov-2 or the vaccine...

tzs 6y ago

Are there any prior mRNA vaccines that have been approved for human use? Wikipedia (currently...) says this and the Moderna ones would be the first.

bluGill 6y ago
There have been a few phase-1 trials in humans. But mostly it is research.

mrosett 6y ago

This isn't entirely true; the technology is still very new.

floatingatoll 6y ago
A five second search finds papers on mRNA vaccines from 2018. I see no papers on Covid prior to 2019. In relative terms, as the parent comment was using, we have been studying them longer. I am not arguing that they are well understood, but I imagine most people are filling in that word when they read the comment.
- abfan1127 6y ago
  We've researched coronaviruses since the 1960s, had MERS and SARS most recently (less recent the 2018). I don't understand why we worry about long term effects of Covid, but not long term effects of mRNA vaccines? Both seem to have things to worry about, with both having different scales. https://www.cdc.gov/coronavirus/types.html https://www.cdc.gov/coronavirus/types.html

just-juan-post 6y ago

100% incorrect. These are the very first mRNA vaccines. Here is Wikiepdia to confirm. [1] You. Are. An. Alpha. Tester. And so is the rest of the world. We all are. https://en.wikipedia.org/wiki/RNA_vaccine https://en.wikipedia.org/wiki/RNA_vaccine "Up until November 2020, no mRNA vaccine, drug, or technology platform, had ever been approved for use in humans, and before 2020, mRNA was only considered a theoretical possibility for effective use in human"

abfan1127 6y ago

why do we get to generalize mRNA vaccines, but not SARS-Cov-2? We've known about coronaviruses since the 1960s, we've had MERS, SARS, and other more recent ones. https://www.cdc.gov/coronavirus/types.html https://www.cdc.gov/coronavirus/types.html I don't think we have long term information on either SARS-Cov-2 or the vaccine...