3 ms·
It's not really a "live" virus - it's an adenovirus (actually, two types of adenovirus) that's been modified so that it can't replicate. The adenoviruses have a
by DiogenesKynikos 6y ago
It's not really a "live" virus - it's an adenovirus (actually, two types of adenovirus) that's been modified so that it can't replicate. The adenoviruses have also been modified to carry the SARS-CoV-2 spike protein.
- baybal2 6y agoNot really, it's not an inactivated adenovirus, just a strain that is much less strong in humans.
- DiogenesKynikos 6y agoThey apparently use what are called "replication-incompetent" or "replication-deficient" vectors: adenoviruses that have been genetically modified to be incapable of (or not very good at - I'm not sure) replicating. Importantly, the vaccine does not use SARS-CoV-2, even in a weakened form. It just presents a SARS-CoV-2 spike protein.