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I suffer from pretty bad depression and have been battling with it for a while using all available treatments. Someone recommended I try psilocybin mushrooms. I

I suffer from pretty bad depression and have been battling with it for a while using all available treatments. Someone recommended I try psilocybin mushrooms. I learned how to grow them, grew them and then had my wife help facilitate a safe well-intentioned trip using 7g of dried mushrooms. Happy to answer any questions about it. It was a profound experience. It isn't a cure but it's certainly a tool in my toolbox that has helped reshaped my life in a real and lasting way.

neitherboosh 6y ago
Wonderful to hear it’s had such a positive impact on your life. What part of the experience made you decide to learn about genetic engineering?
- joshuamcginnis 6y ago
  By serendipity, I discovered a few YouTubers around that time who were showing how to do synthetic biology and biotech step-by-step on the cheap. After the trip, it dawned on me that perhaps I should put my intellectual abilities to work in this new field as it might bring the connection to life and meaning that I've struggled to find in tech.
  - hnmm23 6y ago
    Are those youtubers, or their content still around?
ketzo 6y ago
Sheesh, 7g is no joke. How “hard” was your trip?
- joshuamcginnis 6y ago
  It was difficult and I wouldn't recommend it for newcomers.
  - stef25 6y ago
    Weren't you a (very depressed) newcomer yourself? Don't take it bad but someone in an already bad mental state taking 2g more than what McKenna considered a god dose is pretty ... irresponsible (?)
    - joshuamcginnis 6y ago
      I was depressed, yes. But 7g wasn't my first experience with psilocybin. I was just saying that generally, I would not recommend 7g for newcomers. As for being irresponsible, I don't know man. I grew a Schedule 1 drug and then consumed it on my own terms in a way that affected no one but myself in a positive manner. There were risks involved, but when weighed against how I felt at the time, I took the chance.
      - stef25 6y ago
        Didn't mean to criticize. I've tripped on mushrooms, I get it. It's just ... 7g, holy crap :)
        ericmcer 6y ago
        It’s hard to quantify how strong based purely on dose size, but yeah 7g is double what I would consider a strong dose. I did that amount once in high school and I didn’t touch them again for several years haha.
        tofurocks 6y ago
        People have wildly different reactions, some of my friends can take 14g+ and be fine, others are barely able to talk after 2g. Plus potency varies wildly between crops and strains.
        saiya-jin 6y ago
        Also, there are different types of shrooms, saw at least 7 types last in Amsterdam, potency varied significantly. Also, how empty your stomach is makes world of difference. Also, method of consumption - dried vs fresh, raw/cooked, or like me mixing it with raw lemon juice (makes trip shorter but way more intense - 3g trips were full beyond reality with good setting). Plus individual variation in digestion/enzymes/receptors/god knows what else is most probably also important.
axiom92 6y ago
Thanks!

neitherboosh 6y ago

Wonderful to hear it’s had such a positive impact on your life. What part of the experience made you decide to learn about genetic engineering?

joshuamcginnis 6y ago
By serendipity, I discovered a few YouTubers around that time who were showing how to do synthetic biology and biotech step-by-step on the cheap. After the trip, it dawned on me that perhaps I should put my intellectual abilities to work in this new field as it might bring the connection to life and meaning that I've struggled to find in tech.
- hnmm23 6y ago
  Are those youtubers, or their content still around?

ketzo 6y ago

Sheesh, 7g is no joke. How “hard” was your trip?

joshuamcginnis 6y ago
It was difficult and I wouldn't recommend it for newcomers.
- stef25 6y ago
  Weren't you a (very depressed) newcomer yourself? Don't take it bad but someone in an already bad mental state taking 2g more than what McKenna considered a god dose is pretty ... irresponsible (?)
  - joshuamcginnis 6y ago
    I was depressed, yes. But 7g wasn't my first experience with psilocybin. I was just saying that generally, I would not recommend 7g for newcomers. As for being irresponsible, I don't know man. I grew a Schedule 1 drug and then consumed it on my own terms in a way that affected no one but myself in a positive manner. There were risks involved, but when weighed against how I felt at the time, I took the chance.
    - stef25 6y ago
      Didn't mean to criticize. I've tripped on mushrooms, I get it. It's just ... 7g, holy crap :)
      - ericmcer 6y ago
        It’s hard to quantify how strong based purely on dose size, but yeah 7g is double what I would consider a strong dose. I did that amount once in high school and I didn’t touch them again for several years haha.
        tofurocks 6y ago
        People have wildly different reactions, some of my friends can take 14g+ and be fine, others are barely able to talk after 2g. Plus potency varies wildly between crops and strains.
        saiya-jin 6y ago
        Also, there are different types of shrooms, saw at least 7 types last in Amsterdam, potency varied significantly. Also, how empty your stomach is makes world of difference. Also, method of consumption - dried vs fresh, raw/cooked, or like me mixing it with raw lemon juice (makes trip shorter but way more intense - 3g trips were full beyond reality with good setting). Plus individual variation in digestion/enzymes/receptors/god knows what else is most probably also important.

axiom92 6y ago

Thanks!