6 ms·

>life-changing psychedelic trip Fascinating stuff. Any chance you could expand on this?

joshuamcginnis 6y ago
I suffer from pretty bad depression and have been battling with it for a while using all available treatments. Someone recommended I try psilocybin mushrooms. I learned how to grow them, grew them and then had my wife help facilitate a safe well-intentioned trip using 7g of dried mushrooms. Happy to answer any questions about it. It was a profound experience. It isn't a cure but it's certainly a tool in my toolbox that has helped reshaped my life in a real and lasting way.
- neitherboosh 6y ago
  Wonderful to hear it’s had such a positive impact on your life. What part of the experience made you decide to learn about genetic engineering?
  - joshuamcginnis 6y ago
    By serendipity, I discovered a few YouTubers around that time who were showing how to do synthetic biology and biotech step-by-step on the cheap. After the trip, it dawned on me that perhaps I should put my intellectual abilities to work in this new field as it might bring the connection to life and meaning that I've struggled to find in tech.
    - hnmm23 6y ago
      Are those youtubers, or their content still around?
- ketzo 6y ago
  Sheesh, 7g is no joke. How “hard” was your trip?
  - joshuamcginnis 6y ago
    It was difficult and I wouldn't recommend it for newcomers.
    - stef25 6y ago
      Weren't you a (very depressed) newcomer yourself? Don't take it bad but someone in an already bad mental state taking 2g more than what McKenna considered a god dose is pretty ... irresponsible (?)
      - joshuamcginnis 6y ago
        I was depressed, yes. But 7g wasn't my first experience with psilocybin. I was just saying that generally, I would not recommend 7g for newcomers. As for being irresponsible, I don't know man. I grew a Schedule 1 drug and then consumed it on my own terms in a way that affected no one but myself in a positive manner. There were risks involved, but when weighed against how I felt at the time, I took the chance.
        stef25 6y ago
        Didn't mean to criticize. I've tripped on mushrooms, I get it. It's just ... 7g, holy crap :)
        ericmcer 6y ago
        It’s hard to quantify how strong based purely on dose size, but yeah 7g is double what I would consider a strong dose. I did that amount once in high school and I didn’t touch them again for several years haha.
        tofurocks 6y ago
        People have wildly different reactions, some of my friends can take 14g+ and be fine, others are barely able to talk after 2g. Plus potency varies wildly between crops and strains.
- axiom92 6y ago
  Thanks!
deleted 6y ago
[deleted]
adfm 6y ago
DNA[1] and PCR[2] were both realized while under the influence of LSD. [1]: https://maps.org/research/psilo-lsd/lsd-news-timeline/2054-nobel-prize-genius-crick-was-high-on-lsd-when-he-discovered-dna https://maps.org/research/psilo-lsd/lsd-news-timeline/2054-n... [2]: https://boomcalifornia.org/2015/11/12/on-pcr-lsd-and-science-as-a-wild-ride/ https://boomcalifornia.org/2015/11/12/on-pcr-lsd-and-science...

I suffer from pretty bad depression and have been battling with it for a while using all available treatments. Someone recommended I try psilocybin mushrooms. I learned how to grow them, grew them and then had my wife help facilitate a safe well-intentioned trip using 7g of dried mushrooms. Happy to answer any questions about it. It was a profound experience. It isn't a cure but it's certainly a tool in my toolbox that has helped reshaped my life in a real and lasting way.

neitherboosh 6y ago
Wonderful to hear it’s had such a positive impact on your life. What part of the experience made you decide to learn about genetic engineering?
- joshuamcginnis 6y ago
  By serendipity, I discovered a few YouTubers around that time who were showing how to do synthetic biology and biotech step-by-step on the cheap. After the trip, it dawned on me that perhaps I should put my intellectual abilities to work in this new field as it might bring the connection to life and meaning that I've struggled to find in tech.
  - hnmm23 6y ago
    Are those youtubers, or their content still around?
ketzo 6y ago
Sheesh, 7g is no joke. How “hard” was your trip?
- joshuamcginnis 6y ago
  It was difficult and I wouldn't recommend it for newcomers.
  - stef25 6y ago
    Weren't you a (very depressed) newcomer yourself? Don't take it bad but someone in an already bad mental state taking 2g more than what McKenna considered a god dose is pretty ... irresponsible (?)
    - joshuamcginnis 6y ago
      I was depressed, yes. But 7g wasn't my first experience with psilocybin. I was just saying that generally, I would not recommend 7g for newcomers. As for being irresponsible, I don't know man. I grew a Schedule 1 drug and then consumed it on my own terms in a way that affected no one but myself in a positive manner. There were risks involved, but when weighed against how I felt at the time, I took the chance.
      - stef25 6y ago
        Didn't mean to criticize. I've tripped on mushrooms, I get it. It's just ... 7g, holy crap :)
        ericmcer 6y ago
        It’s hard to quantify how strong based purely on dose size, but yeah 7g is double what I would consider a strong dose. I did that amount once in high school and I didn’t touch them again for several years haha.
        tofurocks 6y ago
        People have wildly different reactions, some of my friends can take 14g+ and be fine, others are barely able to talk after 2g. Plus potency varies wildly between crops and strains.
axiom92 6y ago
Thanks!

deleted 6y ago

[deleted]

adfm 6y ago

DNA[1] and PCR[2] were both realized while under the influence of LSD. [1]: https://maps.org/research/psilo-lsd/lsd-news-timeline/2054-nobel-prize-genius-crick-was-high-on-lsd-when-he-discovered-dna https://maps.org/research/psilo-lsd/lsd-news-timeline/2054-n... [2]: https://boomcalifornia.org/2015/11/12/on-pcr-lsd-and-science-as-a-wild-ride/ https://boomcalifornia.org/2015/11/12/on-pcr-lsd-and-science...