It's much, much, less likely. Half of women with down syndrome are infertile. If they do get pregnant they usually end with a miscarriage and there is a 50% cha

It's much, much, less likely. Half of women with down syndrome are infertile. If they do get pregnant they usually end with a miscarriage and there is a 50% chance the syndrome won't be passed down. Homosapiens are a result of chromosomal fusion, so I would approach the claim of "accruing defects" with great skepticism. Nature is still selecting as evidence by inflicting a high miscarriage & infertility rate. https://www.ndss.org/resources/sexuality/ https://www.ndss.org/resources/sexuality/ https://www.merckmanuals.com/home/children-s-health-issues/chromosome-and-gene-abnormalities/down-syndrome-trisomy-21 https://www.merckmanuals.com/home/children-s-health-issues/c...