There's a game called Rocksmith that has been on the market for many years that basically does this in real time on live guitar playing with far more than enoug

There's a game called Rocksmith that has been on the market for many years that basically does this in real time on live guitar playing with far more than enough accuracy to make the game fun. And that is doing it basically per-note! This task (aligning sheet music with MIDI) would allow for global optimization approaches which should be far easier and more likely to work.