3 ms·
One of my concerns is what happened with the SARS vaccine (meaning, the original SARS.) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335060/ https://www.ncbi.
by Gene_Parmesan 6y ago
One of my concerns is what happened with the SARS vaccine (meaning, the original SARS.)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335060/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335060/
The study described findings of antibody-dependent enhancement with the original SARS. I am no expert, but my understanding is that when test subjects were given the vaccine, and then later 'challenged' by the SARS virus, they developed a pathological response. In other words, taking the vaccine had a potential to make their response to SARS and potentially other coronaviruses worse.
The study I linked therefore recommended caution in giving the vaccine to humans.
Obviously this is something that vaccine researchers are aware of (see https://www.nature.com/articles/s41564-020-00789-5 https://www.nature.com/articles/s41564-020-00789-5), but I think it's something that is perfectly rational to be concerned about given the time and money pressures available with SARS-CoV-2 vaccination.
- inglor_cz 6y agoI believe this entire category of vaccines is no longer considered for human use at all, precisely because of this concerning result.