The first wave of vaccines are destined for frontline and high-risk individuals. They may have a different perspective on the vaccine than your Average Joe, and

The first wave of vaccines are destined for frontline and high-risk individuals. They may have a different perspective on the vaccine than your Average Joe, and I doubt uptake will be a big concern. I don't think distributing and administering will be difficult since it will be on a limited scale. The later rollout to the general public is where most of the problems may be.