I think Fisher's exact test [1] is most commonly used in these types of trials. But the P-value roland (parent comment) provided also make sense to me. For the

I think Fisher's exact test [1] is most commonly used in these types of trials. But the P-value roland (parent comment) provided also make sense to me. For the Fisher's test R says... Covid NoCovid _____ _______ Vaccine 5 1495 NoVaccine 90 1410 9.0e-22 one tailed 4.5e-22 two tailed [1] https://en.wikipedia.org/wiki/Fisher%27s_exact_test https://en.wikipedia.org/wiki/Fisher%27s_exact_test