3 ms·
This lists 2 RCTs (related to Covid-19 + a few others for other infections). One is very small (16 people), the other is dubious, it seems to be the one that co
by hannob 6y ago
This lists 2 RCTs (related to Covid-19 + a few others for other infections). One is very small (16 people), the other is dubious, it seems to be the one that combines with hydroxychloroquine "standard of care". (I believe this was discussed on HN before.)
It almost certainly won't reduce death rate by 25%. Very few medical interventions have an effect size that large.
- chrisco255 6y agohttps://www.sciencedirect.com/science/article/abs/pii/S0960076017300031 https://www.sciencedirect.com/science/article/abs/pii/S09600... Vitamin D levels in summer months are associated with 25% lower mortality rates for all causes. Vitamin D almost certainly influences the immune system to fight off Covid in the same way it does the seasonal flu and other pneumonia. There's hundreds more studies on Vitamin D. Read up when you get a chance. Hell even if it was a 5% reduction we're talking an abundant vitamin that costs pennies to manufacture.
- pjscott 6y ago> the other is dubious, it seems to be the one that combines with hydroxychloroquine "standard of care". I believe you're referring to this one, the RCT run in a hospital in Spain, with a startlingly huge effect size: https://www.sciencedirect.com/science/article/pii/S0960076020302764 https://www.sciencedirect.com/science/article/pii/S096007602... It seems that giving all patients hydroxychloroquine and azithromycin was the policy at that hospital at the time the experiment was run, so the RCT didn't vary that between control and experimental groups; they just gave vitamin D pills to one group and not the other. Is there some problem with this?