4 ms·

Friendly reminder: vitamin D3 can affect sleep if taken later in a day. I tend to skip if I forget to take it before noon. Also, D3 without additional K2 may le

Friendly reminder: vitamin D3 can affect sleep if taken later in a day. I tend to skip if I forget to take it before noon. Also, D3 without additional K2 may lead to calcium excess.

lez 6y ago
One more friendly reminder: If Vitamin D dosage is above 4000IU, same amount of Vitamin A should also be supplemented to avoid Vitamin A deficiency (e.g. eat liver). It's also antiviral, so it sounds like a good idea anyway. More from doctors successfully treating covid with vitamins: https://youtu.be/LwlTQ52Wdro https://youtu.be/LwlTQ52Wdro
- elsonrodriguez 6y ago
  Doctors of "holistic" medicine. One of the people in that video is also a staunch anti-vaxxer. So, broken clocks, and all that.
Aldipower 6y ago
Oh no, 8 hours to late, but thanx for the reminder. ;)
ravedave5 6y ago
From what I googled I couldn't find evidence for Vit D causing sleep issues taken at night - I did find articles suggesting that taking with a meal helps absorbsion - https://www.healthline.com/nutrition/best-time-to-take-vitamin-d#night https://www.healthline.com/nutrition/best-time-to-take-vitam...
- woj-tek 6y ago
  While there are studies on 25-OH-D metabolism impacting melatonin production, I can only find studies done with Multiple Sclerosis patients [1]. There are also studies showing that LOW levels of 25-OH-D may have negative impact on sleep [2][3][4]. While I am unable to present scentific evidence, I would like to state that for me - personally - taking vitamin D3 in the afternoon has similar effects to ingesting caffeine. I have no reason to believe that I might be suffering from Multiple Sclerosis. Without evidence you are free to ignore it as a placebo/nocebo effect. YMMV based on age, ethnicity, sunlight etc. The "take with meal" instruction is common with substances requiring fat for absorption/bioavailability. Dietary fat increases vitamin D3 absorption [5]. [1] https://pubmed.ncbi.nlm.nih.gov/23665342/ https://pubmed.ncbi.nlm.nih.gov/23665342/ The influence of vitamin D supplementation on melatonin status in patients with multiple sclerosis [2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507736/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507736/ 25-Hydroxyvitamin D Concentration and Sleep Duration and Continuity: Multi-Ethnic Study of Atherosclerosis [3] https://pubmed.ncbi.nlm.nih.gov/28652922/ https://pubmed.ncbi.nlm.nih.gov/28652922/ The relationship between serum vitamin D levels and sleep quality in fixed day indoor field workers in the electronics manufacturing industry in Korea [4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331570/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331570/ Association between Serum Vitamin D Levels and Sleep Disturbance in Hemodialysis Patients [5] https://pubmed.ncbi.nlm.nih.gov/25441954/ https://pubmed.ncbi.nlm.nih.gov/25441954/ Dietary fat increases vitamin D-3 absorption

Friendly reminder: vitamin D3 can affect sleep if taken later in a day. I tend to skip if I forget to take it before noon. Also, D3 without additional K2 may lead to calcium excess.

lez 6y ago

One more friendly reminder: If Vitamin D dosage is above 4000IU, same amount of Vitamin A should also be supplemented to avoid Vitamin A deficiency (e.g. eat liver). It's also antiviral, so it sounds like a good idea anyway. More from doctors successfully treating covid with vitamins: https://youtu.be/LwlTQ52Wdro https://youtu.be/LwlTQ52Wdro

elsonrodriguez 6y ago
Doctors of "holistic" medicine. One of the people in that video is also a staunch anti-vaxxer. So, broken clocks, and all that.

Aldipower 6y ago

Oh no, 8 hours to late, but thanx for the reminder. ;)

ravedave5 6y ago

From what I googled I couldn't find evidence for Vit D causing sleep issues taken at night - I did find articles suggesting that taking with a meal helps absorbsion - https://www.healthline.com/nutrition/best-time-to-take-vitamin-d#night https://www.healthline.com/nutrition/best-time-to-take-vitam...

woj-tek 6y ago
While there are studies on 25-OH-D metabolism impacting melatonin production, I can only find studies done with Multiple Sclerosis patients [1]. There are also studies showing that LOW levels of 25-OH-D may have negative impact on sleep [2][3][4]. While I am unable to present scentific evidence, I would like to state that for me - personally - taking vitamin D3 in the afternoon has similar effects to ingesting caffeine. I have no reason to believe that I might be suffering from Multiple Sclerosis. Without evidence you are free to ignore it as a placebo/nocebo effect. YMMV based on age, ethnicity, sunlight etc. The "take with meal" instruction is common with substances requiring fat for absorption/bioavailability. Dietary fat increases vitamin D3 absorption [5]. [1] https://pubmed.ncbi.nlm.nih.gov/23665342/ https://pubmed.ncbi.nlm.nih.gov/23665342/ The influence of vitamin D supplementation on melatonin status in patients with multiple sclerosis [2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507736/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507736/ 25-Hydroxyvitamin D Concentration and Sleep Duration and Continuity: Multi-Ethnic Study of Atherosclerosis [3] https://pubmed.ncbi.nlm.nih.gov/28652922/ https://pubmed.ncbi.nlm.nih.gov/28652922/ The relationship between serum vitamin D levels and sleep quality in fixed day indoor field workers in the electronics manufacturing industry in Korea [4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331570/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331570/ Association between Serum Vitamin D Levels and Sleep Disturbance in Hemodialysis Patients [5] https://pubmed.ncbi.nlm.nih.gov/25441954/ https://pubmed.ncbi.nlm.nih.gov/25441954/ Dietary fat increases vitamin D-3 absorption