3 ms·
Anyone know the difference in delivery mechanism between these two? Both are mRNA right?
by abacadaba 6y ago
Anyone know the difference in delivery mechanism between these two? Both are mRNA right?
- aphextron 6y ago>Anyone know the difference in delivery mechanism between these two? Both are mRNA right? They're extremely similar. Both are mRNA delivered via lipid nanoparticle vector.
- dnautics 6y agoWho knows. Almost all therapeutic rnas have unnatural RNA bases or base linkages that are, for example, resistant to internal phosphatases/autohydrolysis to improve half life; half life can also depend on secondary structure, and of course as a sibling comment mentioned, it can depend on the stability of the lipid nanoparticles.