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CRISPR is currently being used to treat human subjects in these clinical trials: * Transthyretin Amyloidosis: https://news.yahoo.com/intellia-therapeutics-dose
by Areading314 6y ago
CRISPR is currently being used to treat human subjects in these clinical trials:
* Transthyretin Amyloidosis: https://news.yahoo.com/intellia-therapeutics-doses-first-patient-123000978.html https://news.yahoo.com/intellia-therapeutics-doses-first-pat...
* Lymphoma: https://www.healio.com/news/hematology-oncology/20201023/crispredited-allogeneic-cart-demonstrates-activity-in-advanced-lymphoma https://www.healio.com/news/hematology-oncology/20201023/cri...
* Leber Congenital Amaurosis: https://www.retina-international.org/lca-10-clinical-trial-first-patient-treated-with-crispr/ https://www.retina-international.org/lca-10-clinical-trial-f...
* Thalassemia & Sickle Cell: https://geneticliteracyproject.org/2020/06/18/crispr-provides-functional-cure-for-patients-with-beta-thalassemia-sickle-cell-disease-preliminary-study-shows/ https://geneticliteracyproject.org/2020/06/18/crispr-provide...
* Antibiotic Resistant UTIs: https://www.medpace.com/the-first-controlled-clinical-trial-for-a-crispr-enhanced-bacteriophage-therapy/ https://www.medpace.com/the-first-controlled-clinical-trial-...
- light_hue_1 6y agoTrials take a long time but some early results are pretty amazing. For example for the Thalassemia & Sickle Cell trial we actually have patients that have been treated with great results https://crisprtx.gcs-web.com/news-releases/news-release-details/crispr-therapeutics-and-vertex-announce-new-clinical-data https://crisprtx.gcs-web.com/news-releases/news-release-deta... Physicians running the trial claim that these diseases are basically cured in some patients: “I am encouraged by the preliminary results, which demonstrate, in essence, a functional cure for patients with beta thalassemia and sickle cell disease.” This is just the beginning. The article is clickbait, or worse, totally misinformed.
- throwaway2245 6y ago> This is just the beginning. A vaccines to eradicate smallpox was discovered in 1796. Since then 1 (one) eradicating vaccine has been produced. I'd assume, in agreement with the headline, that the value of CRISPR has already been identified. That's how biological breakthroughs historically are.