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There are least two supplements for which it's probably unnecessary to test for deficiency to know that supplementation may be helpful under certain conditions:

There are least two supplements for which it's probably unnecessary to test for deficiency to know that supplementation may be helpful under certain conditions: * Vitamin D (for certain races, and for people with a mostly sedentary lifestyle in countries where exposure to sunlight is low) * B12 (vegans) Disclaimer: I am not a medical professional.

treeman79 6y ago
Magnesium tends to be high up. Amazing stuff.
- arcticbull 6y ago
  I highly recommend checking into any supplements you consider taking to see if there's supporting data. This visualization is great, and I think I found out about it here, incidentally [1]. As you'll find there, there's little evidence magnesium supplementation does anything for general wellness. Vitamin D and Calcium for bone health, sure, there's good evidence for that. [1] http://www.informationisbeautiful.net/play/snake-oil-supplements/ http://www.informationisbeautiful.net/play/snake-oil-supplem...
  - treeman79 6y ago
    Studies are crap. Stuff is life altering, if you need it. 50% reduction in migraines, sharp drop in aches and pains. Supper my groups are full of success stories. I’ve had multiple Neurologist recommend it as a starting point. If your feeling fine to begin with. It’s probably not going to do a thing.
    - arcticbull 6y ago
      > Studies are crap. Ok, that's not how science works. > Stuff is life altering, if you need it. And if so, it'll show up in a study. > 50% reduction in migraines, sharp drop in aches and pains. Supper my groups are full of success stories. That's great, and it's supported by... wait for it... studies [1] "Magnesium's role in migraine pathogenesis is well-described, with deficiencies known to promote cortical spreading depression, alter nociceptive processing and neurotransmitter release, and encourage the hyperaggregation of platelets, all major elements of migraine development." If you have a defined deficiency, then a specific vitamin may be helpful. If there's nothing wrong with you, then it's at best neutral, and at worst harmful -- and expensive. We need to take a science-forward approach to this stuff. [edit] To be clear: you didn't mention specifically what you were using magnesium for, and the parent post was implying that there were vitamins or minerals that it wasn't worth checking whether you had the deficiency before taking. As such I looked into the role of magnesium in general wellness which is not supported by data. Had you mentioned that it was for a specific condition, I would have researched it before making my implication, so my bad there. [1] https://www.ncbi.nlm.nih.gov/books/NBK507271/ https://www.ncbi.nlm.nih.gov/books/NBK507271/

treeman79 6y ago

Magnesium tends to be high up. Amazing stuff.

arcticbull 6y ago
I highly recommend checking into any supplements you consider taking to see if there's supporting data. This visualization is great, and I think I found out about it here, incidentally [1]. As you'll find there, there's little evidence magnesium supplementation does anything for general wellness. Vitamin D and Calcium for bone health, sure, there's good evidence for that. [1] http://www.informationisbeautiful.net/play/snake-oil-supplements/ http://www.informationisbeautiful.net/play/snake-oil-supplem...
- treeman79 6y ago
  Studies are crap. Stuff is life altering, if you need it. 50% reduction in migraines, sharp drop in aches and pains. Supper my groups are full of success stories. I’ve had multiple Neurologist recommend it as a starting point. If your feeling fine to begin with. It’s probably not going to do a thing.
  - arcticbull 6y ago
    > Studies are crap. Ok, that's not how science works. > Stuff is life altering, if you need it. And if so, it'll show up in a study. > 50% reduction in migraines, sharp drop in aches and pains. Supper my groups are full of success stories. That's great, and it's supported by... wait for it... studies [1] "Magnesium's role in migraine pathogenesis is well-described, with deficiencies known to promote cortical spreading depression, alter nociceptive processing and neurotransmitter release, and encourage the hyperaggregation of platelets, all major elements of migraine development." If you have a defined deficiency, then a specific vitamin may be helpful. If there's nothing wrong with you, then it's at best neutral, and at worst harmful -- and expensive. We need to take a science-forward approach to this stuff. [edit] To be clear: you didn't mention specifically what you were using magnesium for, and the parent post was implying that there were vitamins or minerals that it wasn't worth checking whether you had the deficiency before taking. As such I looked into the role of magnesium in general wellness which is not supported by data. Had you mentioned that it was for a specific condition, I would have researched it before making my implication, so my bad there. [1] https://www.ncbi.nlm.nih.gov/books/NBK507271/ https://www.ncbi.nlm.nih.gov/books/NBK507271/