5 ms·
Pfizer's press release with more information: https://www.businesswire.com/news/home/20201109005539/en/ https://www.businesswire.com/news/home/20201109005539/en
by y7 6y ago
Pfizer's press release with more information: https://www.businesswire.com/news/home/20201109005539/en/ https://www.businesswire.com/news/home/20201109005539/en/
- Vaccine candidate was found to be more than 90% effective in preventing COVID-19 in participants without evidence of prior SARS-CoV-2 infection in the first interim efficacy analysis
- Analysis evaluated 94 confirmed cases of COVID-19 in trial participants
- Study enrolled 43,538 participants, with 42% having diverse backgrounds, and no serious safety concerns have been observed; Safety and additional efficacy data continue to be collected
- Submission for Emergency Use Authorization (EUA) to the U.S. Food and Drug Administration (FDA) planned for soon after the required safety milestone is achieved, which is currently expected to occur in the third week of November
- Clinical trial to continue through to final analysis at 164 confirmed cases in order to collect further data and characterize the vaccine candidate’s performance against other study endpoints
- collyw 6y ago"diverse backgrounds" What does that mean exactly? Surely a random sample of people will have diverse backgrounds.
- turing_complete 6y agoI found that strange too. Diverse is a relative term, not an absolute one.
- rimliu 6y agoRandom sample of women aged 19-30 would be less diverse than random sample from anybody.
- lbeltrame 6y agoIt means that it includes people from different ethnicity, ages (also younger and older people) and some immunocompromised people.
- cblconfederate 6y agoshouldnt they be focusing on older people? in fact if they are first to be vaccinated the fatality would drop very very significantly
- lbeltrame 6y agoThe 56-85 age bracket is 45% of the volounteers tested, according to Pfizer.
- stu2b50 6y agoYou want to have at least a nontrivial group of every race and ethnicity to ensure that you collect enough data to make sure it's also effective on everyone. Additional challenges in the US are that many minority communities are distrustful of the pharmaceutical industry due to historical reasons and you typically need a concentrated effort to do outreach there to actually collect enough volunteers to meet your sampling concerns.
- ggghhhfff 6y agoRandom sample != representative sample