3 ms·
> What are the problems with earlier stage screening? It's not false positives that are the issue. It's the huge number of false negatives. The standard biomar
by selectodude 6y ago
> What are the problems with earlier stage screening?
It's not false positives that are the issue. It's the huge number of false negatives. The standard biomarker we look for is only present in 70 percent of people with the cancer. Furthermore, only 5 percent of the people who present with CA 19-9 even have pancreatic cancer to begin with since it also presents with almost any other gut issue.
>which is a failure of the medical system rather than a deficiency in the medical technology.
The technology that we have to actually find pancreatic cancer is an endoscopy which is going to find a whole lot of stuff. 5 percent of the issues present on your pancreas are pancreatic cancer.
>Is early diagnosis of pancreatic cancer something like this that needs to be fixed in the "system" or just something we don't have the technology to do?
We simply don't have the technology. Below is a link with a bunch of statistics showing just how devilishly hard pancreatic cancer is to find before metastasis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113008/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113008/