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Muscle mass alone isn't enough. Obese people have far less aerobic headroom (lower VO2_max per kg), so viral pneumonia that decreases their lung efficiency even
by Scaevolus 6y ago
Muscle mass alone isn't enough. Obese people have far less aerobic headroom (lower VO2_max per kg), so viral pneumonia that decreases their lung efficiency even further is harder to survive.
There are many factors:
"Fat in the abdomen pushes up on the diaphragm, causing that large muscle, which lies below the chest cavity, to impinge on the lungs and restrict airflow."
"the blood of people with obesity has an increased tendency to clot—an especially grave risk during an infection that, when severe, independently peppers the small vessels of the lungs with clots"
"Immunity also weakens in people with obesity, in part because fat cells infiltrate the organs where immune cells are produced and stored"
"people with obesity also suffer from chronic, low-grade inflammation... Those effects may compound the runaway cytokine activity that characterizes severe COVID-19"
https://www.sciencemag.org/news/2020/09/why-covid-19-more-deadly-people-obesity-even-if-theyre-young https://www.sciencemag.org/news/2020/09/why-covid-19-more-de...
- skywhopper 6y agoBMI says nothing about fat percentage.
- Scaevolus 6y agoIt's an incredibly strong correlation. Very few people with BMI over 30 have under 30% body fat: https://www.researchgate.net/figure/BMI-versus-total-body-fat-percentage-based-on-muscle-mass-status-and-age-Graphs-show_fig1_324466220 https://www.researchgate.net/figure/BMI-versus-total-body-fa... There are some exceptions like professional bodybuilders (often with the aid of steroids), but we're talking about reasons why mortality rates are linked to BMI, not declaring absolutes.
- im3w1l 6y agoI agree with you, just want to say I think the reason skywhooper is bringing it up is "you get what you measure" and that hard rules about BMI risks harming and disincentivizing the body building community.