I guess (I'm no expert) we would want a little of both: A blind, Niacin trial that is not placebo controlled AND a Placebo controlled but not blind trial? I won

I guess (I'm no expert) we would want a little of both: A blind, Niacin trial that is not placebo controlled AND a Placebo controlled but not blind trial? I wonder what Tim Ferriss has gotten up to recently on this...