3 ms·

I’m confused by this comment. There is evidence that Vit D deficiencies have all sorts of health impacts, and that supplements raise in-blood levels. What other

I’m confused by this comment. There is evidence that Vit D deficiencies have all sorts of health impacts, and that supplements raise in-blood levels. What other evidence is needed? https://www.bulletproof.com/supplements/vitamins-minerals/vitamin-d-optimal-range/ https://www.bulletproof.com/supplements/vitamins-minerals/vi... (11 scientific references linked at the bottom)

dan-robertson 6y ago
Most things related to vitamin D are just correlation. If you are weak and frail you may not get out much and won’t have so much vitamin D. That doesn’t mean giving you vitamin D will make you strong. I heard that most studies don’t show benefits from vitamin D a supplements but maybe I’m wrong.
- joshspankit 6y ago
  Sounds to me like what you heard could be easily proven/disproven by reading some studies.
  - dan-robertson 6y ago
    I searched google scholar for “vitamin d meta analysis”. I skimmed the abstracts. These are some of the earlier results. It seems supplements help but randomised controlled trials are needed: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/413032 https://jamanetwork.com/journals/jamainternalmedicine/fullar... “Vitamin D supplementation appears to reduce the risk of falls among ambulatory or institutionalized older individuals with stable health by more than 20%” http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.578.2134&rep=rep1&type=pdf http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.578... Oral vitamin D supplementation between 700 to 800 IU/d appears to reduce the risk of hip and any nonvertebral fractures in ambulatory or institutionalized elderly persons. An oral vitamin D dose of 400 IU/d is not sufficient for fracture prevention. https://jamanetwork.com/journals/jama/article-abstract/200871 https://jamanetwork.com/journals/jama/article-abstract/20087... High levels of vitamin D among middle-age and elderly populations are associated with a substantial decrease in cardiovascular disease, type 2 diabetes and metabolic syndrome. If the relationship proves to be causal, interventions targeting vitamin D deficiency in adult populations could potentially slow the current epidemics of cardiometabolic disorders. https://www.sciencedirect.com/science/article/abs/pii/S037851220900468X https://www.sciencedirect.com/science/article/abs/pii/S03785... ———————————— At this point I got bored of looking at results (I omitted a few which only looked for correlations). So while there is some evidence of some benefits for some people, I didn’t find evidence of vitamin d being the magic panacea that it sometimes feels it is claimed to be by people on the internet.
    - def_true_false 6y ago
      Well, if it may have benefits and costs pretty much nothing, it would make sense to take it...

dan-robertson 6y ago

Most things related to vitamin D are just correlation. If you are weak and frail you may not get out much and won’t have so much vitamin D. That doesn’t mean giving you vitamin D will make you strong. I heard that most studies don’t show benefits from vitamin D a supplements but maybe I’m wrong.

joshspankit 6y ago
Sounds to me like what you heard could be easily proven/disproven by reading some studies.
- dan-robertson 6y ago
  I searched google scholar for “vitamin d meta analysis”. I skimmed the abstracts. These are some of the earlier results. It seems supplements help but randomised controlled trials are needed: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/413032 https://jamanetwork.com/journals/jamainternalmedicine/fullar... “Vitamin D supplementation appears to reduce the risk of falls among ambulatory or institutionalized older individuals with stable health by more than 20%” http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.578.2134&rep=rep1&type=pdf http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.578... Oral vitamin D supplementation between 700 to 800 IU/d appears to reduce the risk of hip and any nonvertebral fractures in ambulatory or institutionalized elderly persons. An oral vitamin D dose of 400 IU/d is not sufficient for fracture prevention. https://jamanetwork.com/journals/jama/article-abstract/200871 https://jamanetwork.com/journals/jama/article-abstract/20087... High levels of vitamin D among middle-age and elderly populations are associated with a substantial decrease in cardiovascular disease, type 2 diabetes and metabolic syndrome. If the relationship proves to be causal, interventions targeting vitamin D deficiency in adult populations could potentially slow the current epidemics of cardiometabolic disorders. https://www.sciencedirect.com/science/article/abs/pii/S037851220900468X https://www.sciencedirect.com/science/article/abs/pii/S03785... ———————————— At this point I got bored of looking at results (I omitted a few which only looked for correlations). So while there is some evidence of some benefits for some people, I didn’t find evidence of vitamin d being the magic panacea that it sometimes feels it is claimed to be by people on the internet.
  - def_true_false 6y ago
    Well, if it may have benefits and costs pretty much nothing, it would make sense to take it...