Yes, and if you have different versions of the HLA gene, you get different distributions as a result of V(D)J recombination. So, in a way, different individual

Yes, and if you have different versions of the HLA gene, you get different distributions as a result of V(D)J recombination. So, in a way, different individuals have different immune strategies. For example, super-responders to HIV tend to be HLA-B57. This HLA "version" trades better response to virus that mutate quickly for more chances of autoimmunity as thymic selection is less stringent (because HLA-B57 presents less selfpeptides in the thymus).