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I feel like the term intermittent fasting is used by many folks to mean different things. It would be nice if there were more precise terminology here so we cou

• diydsp 6y ago
  From the fine article: >We evaluated the impact of 3 months of IF (12, 16, and 24 hr of food deprivation on a daily basis)
  • rottencupcakes 6y ago
    Super interested in how the mice who experienced daily 24 hr food deprivation for 3 months did in the study.
    • ei8htyfi5e 6y ago
      They eat once a day... so I’m sure they’re fine...
      • waihtis 6y ago
        Fun fact: Mice can only survive 48 hours without food, so not eating for 24 hours is quite long for them.
        • treeman79 6y ago
          Had recently gotten two mice. We were upstairs when we realized it was the first ice cold night of the year. So we went down and mice are cuddled in the cold , and apparently out of food. Someone decided fruit loops mixed in with mouse food was a good idea. One mouse went and ate. Other one was clearly in roughed shap. First mouse took a fruit loop, walked it over, and kept putting it against the others mouth. After couple minutes she started eating. The sheer empathy of one mouse helping another still gets to me. They both were fine after eating and being moved to a warm spot.
        • eznzt 6y ago
          What determines how long you can survive without food? The speed of your metabolism?
          • fpoling 6y ago
            Mostly how much fat and muscle tissue one has. The known record under medical supervision is over a year, but that person was very fat at the start.
    • sfourdrinier 6y ago
      actually there are studies especially from David Sinclair that shows that fasting and calorie restrictions help mice live longer and healthier. For those interested here is a great interview with David Sinclair, Harvard Researcher on aging: https://www.youtube.com/watch?v=8ZqAKNPxaxc https://www.youtube.com/watch?v=8ZqAKNPxaxc
      • fredophile 6y ago
        I'm very skeptical of any diet related advice based on studying mice. Mouse metabolism is very different from human metabolism.. Fasting a mouse for 24 hours will result in a fairly large loss of body mass. Fasting a person for 24 hours will result in a pound or two of weight loss. I'm not against doing these kinds of studies on mice but the only conclusion you can really get is that we should do longer studies on animals that are closer to humans or on humans themselves.
        • thesz 6y ago
          Pound of fat, or, in SI, 453 grams of fat, is 4077 calories (9 calories per gram of fat). Most probably, weight loss will be less than pound in water calorie restriction. Also, there was studies on Ramadan fasting and they've found almost two fold increase of serum brain-derived neurotrophic factor at the end of fast. Level of BDNF correlates with neuroneogenesis in brain.
  • phaemon 6y ago
    I'm pretty sure that "24 hr of food deprivation on a daily basis" would leave you dead!
    • drewbug 6y ago
      can stuff themselves on leap seconds
      • bbarnett 6y ago
        I've drank canned chilli, and I bet if super motivated I could drink a can in a second. Sadly, leap seconds are rare.
  • csomar 6y ago
    If 12H is considered IF, then I have been intermittently fasting for the last 4-5 years.
    • TuringNYC 6y ago
      From everything I've read, it is on a spectrum. 12 is on the spectrum, but supposedly the longer the period the more marked the effects. I'm not sure at what point the curve flattens and drops off. 12 is better than, say, 8 or 6 (e.g., snacking at night). Curious how your experience compares to your pre-IF state 5+yrs ago?
      • csomar 6y ago
        I don't know. I know that I'm more miserable than ever but that's an emotional state. So I guess the answer is: non-noticeable.
      • ip26 6y ago
        There's a point it becomes destructive. I tend to ignore hunger, and I find after 20 hours or so my mood nosedives, I get shaky, generally things go south quickly and even if I eat I'm still a wreck for a while. 12-16hrs is probably the sweet spot from my experience. BMI 18-19 for reference.
        • TuringNYC 6y ago
          Your IF experience sounds hard, is IF worth it for you? Would you mind sharing your BMI from before IF? Also curious if you feel IF is better than the alternatives (e.g., Keto, which for me has been the "easiest" of the effective diets)
          • ip26 6y ago
            Oh IF is just how I have generally lived my life, long before it was "a thing". So not much to compare. I did have a really good experience doing long fasted running in the morning. At first I couldn't go three miles without breakfast. But eventually I could do twelve straight out of bed and feel great. As I understand, fasting trains your body to supply blood glucose from fat stores, which breaks your brain's craving for sugary foods- which are a crutch for getting your blood sugar up. (Remember, your brain runs mainly on blood glucose) Keto does the same thing a different way. But to me IF is way easier and healthier. (I strive to eat a Mediterranean style diet which ain't Keto!) I would say the experience for me is really good- as long as I avoid the cliff, which is what I was warning about. Basically, just don't try to get all extreme thinking longer fasts are always better.
  • trhway 6y ago
    >>12, 16, and 24 hr of food deprivation on a daily basis given different metabolism speed and body energy stores depletion rate that would translate into days for humans. Sidenote: it is not a good thing to torture animals.